Thermo Fisher Scientific MOS Polyclonal Antibody
Thermo Fisher Scientific의 MOS Polyclonal Antibody는 인간 MOS 단백질을 인식하는 토끼 유래 다클론 항체입니다. Western blot 및 IHC(P) 실험에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 기반 완충액에 40% 글리세롤이 포함되어 장기 보관이 용이합니다.
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MOS. Recombinant protein control fragment (Product #RP-96532). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644058 |
Product Specific Information
Immunogen sequence:
CKISDFGCSE KLEDLLCFQT PSYPLGGTYT HRAPELLKGE GVTPKADIYS FAITLWQMTT KQAPYSGERQ HILYAVVAYD LRPSLSAAVF
Highest antigen sequence identity:
- Mouse: 72%
- Rat: 73%
Target Information
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the γ phosphate of ATP, onto an acceptor amino acid in a substrate protein. Through this mechanism, protein kinases mediate most signal transduction in eukaryotic cells, regulating processes such as metabolism, transcription, cell cycle progression, cytoskeletal rearrangement, cell movement, apoptosis, and differentiation.
With more than 500 gene products, the protein kinase family is one of the largest in eukaryotes. They are classified into 8 major groups based on sequence comparison of tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) includes 50 kinases related to the MAPK cascade families (Ste7/MAP2K, Ste11/MAP3K, Ste20/MAP4K). MAP kinase cascades, composed of a MAPK and one or more upstream kinases (MAPKKs), are well characterized in the yeast pheromone response pathway, where pheromones activate the MAPK pathway via Ste cell surface receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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