Thermo Fisher Scientific REG1B Recombinant Rabbit Monoclonal Antibody (029)

Applications

• ELISA (ELISA)
  • Tested Dilution: 1:5,000–1:10,000

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The specific antibody DNA sequences from immunoreactive rabbits are cloned, and individual clones are screened to select the best candidates for production.

Advantages of recombinant rabbit monoclonal antibodies:

• Improved specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulation
• Broader immunoreactivity due to the rabbit immune repertoire

This antibody is specific for Human REG1B.

Target Information

REG1B may act as an inhibitor of spontaneous calcium carbonate precipitation. It may be associated with neuronal sprouting in the brain and with brain and pancreas regeneration.

This gene belongs to the Reg gene family, a multigene family grouped into four subclasses (types I–IV) based on the primary structures of the encoded proteins. The REG1B gene encodes a protein secreted by the exocrine pancreas, highly similar to REG1A. REG1A is associated with islet cell regeneration and diabetogenesis and may be involved in pancreatic lithogenesis. Reg family members REG1A, REGL, PAP, and REG1B are tandemly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by duplication.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.