Thermo Fisher Scientific NTAL Polyclonal Antibody
Rabbit polyclonal antibody targeting human NTAL (aa 91-243), validated for WB and IHC applications. Recognizes human NTAL without cross-reactivity to mouse. Supplied as liquid, unconjugated form, stored at 4°C. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant cytoplasmic domain (aa 91–243) of human NTAL |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Wet ice |
| RRID | AB_2234393 |
Product Specific Information
This antibody recognizes the defined epitope (aa 91–243) of human Non-T cell Activation Linker (NTAL). It will not cross-react with mouse.
Target Information
NTAL (Non-T cell Activation Linker), also known as LAB (Linker for activation of B cells), is a 30 kDa double-palmitoylated transmembrane adaptor protein expressed by B cells, NK cells, mast cells, and macrophages. It acts as a negative regulator of early stages of BCR-dependent B cell signaling and also functions as a negative regulator in mast cells. In mast cells, NTAL contributes to certain activation processes, partially overlapping with LAT function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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