Thermo Fisher Scientific NTAL Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

-

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant cytoplasmic domain (aa 91-243) of human NTAL. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NTAL,uniProtId:Q9GZY6-1,ncbiNodeId:9606,antigenRange:91-243,antigenLength:243,antigenImageFileName:PA1-19440_NTAL_Q9GZY6-1_Rabbit.svg,antigenImageFileNamePDP:PA1-19440_NTAL_Q9GZY6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Storage conditions

4° C, do not freeze

Shipping conditions

Wet ice

RRID

AB_2234393

Product Specific Information

This antibody recognizes the defined epitope (aa 91-243) of human Non-T cell Activation Linker (NTAL). It will not cross-react with mouse.

Target Information

NTAL (Non-T cell Activation Linker), also known as LAB (Linker for activation of B cells), is a 30 kDa double-palmitoylated transmembrane adaptor protein expressed by B cells, NK cells, mast cells and macrophages. It is a negative regulator of early stages of BCR-dependent B cell signaling and serves as a negative regulator also in mast cells. However, in mast cells, NTAL also contributes to some activation processes, partially overlapping with LAT function.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.