Thermo Fisher Scientific IL23R Polyclonal Antibody
IL23R 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, Flow Cytometry에 적합. Human 및 Mouse 반응성. Protein G로 정제된 액상 형태이며 PBS buffer에 0.05% sodium azide 포함. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–1.0 µg/mL |
| Immunohistochemistry (IHC) | 5–10 µg/mL |
| Flow Cytometry (Flow) | 1:10–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide located at amino acids 439–455 of human IL-23R (NP_653302) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2718794 |
Target Information
IL-23R is a 629 amino acid novel subunit of the receptor for cytokine IL23A/IL23, which pairs with IL12RB1/IL12R beta 1 and participates in IL23A signaling. It associates constitutively with Janus kinase 2 (JAK2) and binds to transcription activator STAT3 in a ligand-dependent manner. Alternative splicing results in six isoforms of IL-23R. Reports suggest IL-23R plays an important role in psoriasis pathogenesis and may be a therapeutic target in inflammatory bowel disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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