Thermo Fisher Scientific TrkCT1 Polyclonal Antibody
TrkCT1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, ELISA, IP에 적합합니다. Human, Mouse, Rat에 반응하며, Affinity chromatography로 정제되었습니다. 액상 형태로 -20°C에서 보관하며 연구용으로 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 |
| ELISA | 1:5,000–1:20,000 |
| Immunoprecipitation (IP) | 1 µg |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Affinity purified antibody prepared from whole rabbit serum immunized with a synthetic peptide corresponding to amino acids near the carboxyl terminus of mouse TrkCT1 protein. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Store vial at -20°C prior to opening.
- Aliquot contents and freeze at -20°C or below for extended storage.
- Avoid repeated freeze/thaw cycles.
- Centrifuge if not completely clear after standing at room temperature.
- Stable for several weeks at 4°C as an undiluted liquid.
- Dilute only prior to immediate use.
This antibody is directed against mouse TrkCT1 protein. BLAST analysis suggests cross-reactivity with TrkCT1 protein from human, mouse, and rat based on 100% homology with the immunizing sequence. Reactivity with homologues from other species is not known.
Target Information
NTRK3 (TRKC) belongs to the neurotrophic factor family, essential for development and maintenance of the mammalian nervous system. Known substrates include SHC, PI-3 kinase, and PLCG1. Isoforms differ in signaling properties, and expression is predominant in nervous tissue. Isoform B is more abundant in adult brain than fetal brain. TRKC undergoes ligand-mediated auto-phosphorylation and contains two immunoglobulin-like C2-type domains and two leucine-rich (LRR) repeats.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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