Thermo Fisher Scientific Angiopoietin 1 Polyclonal Antibody
Thermo Fisher Scientific의 Angiopoietin 1 폴리클로날 항체는 인간 및 생쥐에 반응하며, 혈관 발달 연구에 적합합니다. WB, IHC, ELISA 등 다양한 응용 가능. 고농도(80 mg/mL) 액상 형태로 제공되며, 장기 보관 시 -20°C에서 안정적입니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:800 | - |
| ELISA | 1:5,000–1:25,000 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the N-terminus residues CN(21) Q R R N P E N G G R R Y N R I Q H G Q(40) of mouse Ang-1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 80 mg/mL |
| Storage Buffer | 0.02M potassium phosphate/whole serum, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2227195 |
Product Specific Information
This antibody is specific for mouse Angiopoietin 1 (mAng-1). Partial cross-reactivity is noted with human Angiopoietin 2. Store as a concentrated solution. Centrifuge briefly prior to opening vial.
Target Information
Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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