Thermo Fisher Scientific DYRK1A Polyclonal Antibody
DYRK1A 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, ICC/IF, IP에 사용 가능. Human 및 Mouse 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. 세포 증식 관련 연구 및 다운증후군 관련 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Immunoprecipitation (IP) | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to human DYRK1A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 27 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10985691 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
DYRK1A is a dual specificity kinase involved in cell proliferation. The gene for DYRK1A is located in the Down syndrome critical region of chromosome 21 and has been implicated in the pathogenesis of this disease. DYRK1A catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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