Thermo Fisher Scientific SMARCB1 Polyclonal Antibody
SMARCB1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat에 반응합니다. WB, IHC, ICC/IF 등 다양한 응용에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능하며, 장기 보관 시 -20°C에서 보관 권장.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SMARCB1. Recombinant protein control fragment (Product #RP-92347) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647611 |
Product Specific Information
Immunogen sequence:
SVTLLKASEV EEILDGNDEK YKAVSISTEP PTYLREQKAK RNSQWVPTLP NSSHHLDAVP CSTTINRNRM GRDKKRTFPL CFDDHDPAVI HENASQPE
Highest antigen sequence identity to the following orthologs:
- Mouse: 100%
- Rat: 100%
Target Information
The SWI-SNF complex is involved in transcription activation via nucleosome remodeling in an ATP-dependent manner. Brm (SNF2alpha) and Brg-1 (SNF2beta) are ATPase subunits of the mammalian SWI-SNF complex. Brm, Brg-1, Ini1 (SNF5), BAF155 (SRG3), and BAF170 form the functional core of the complex. Addition of Ini1, BAF155, and BAF170 enhances remodeling activity, while other subunits play regulatory roles. hSNF2L and hSNF2H are homologs of Drosophila ISWI, present in chromatin remodeling complexes other than SWI/SNF, such as NURF.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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