Thermo Fisher Scientific FLT4 Monoclonal Antibody (5F11)
FLT4 단클론 항체(5F11)는 인간 FLT4 단백질을 표적으로 하는 마우스 IgG2a 항체로, Western blot 및 ELISA에 적합합니다. 친화 크로마토그래피로 정제되었으며, PBS(pH 7.4) 용액에 보존제 없이 제공됩니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific FLT4 Monoclonal Antibody (5F11)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5F11 |
| Immunogen | FLT4 (NP_002011, 34–133 a.a.) partial recombinant protein with GST tag (MW of GST tag alone: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
ITEESHVIDT GDSLSISCRG QHPLEWAWPG AQEAPATGDK DSEDTGVVRD CEGTDARPYC KVLLLHEVHA NDTGSYVCYY KYIKARIEGT TAASSYVFVR
Target Information
Vascular endothelial growth factor (VEGF) is a key regulator of blood vessel development in embryos and angiogenesis in adult tissues.
VEGFC specifically stimulates lymphatic vessel growth via its receptor VEGFR-3.
Inactivation of VEGFR-3 in mice results in defective blood vessel development, abnormal lumen formation, and cardiovascular failure at embryonic day 9.5.
Thus, VEGFR-3 plays an essential role in embryonic cardiovascular development prior to lymphatic vessel formation.
Usage Note
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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