Thermo Fisher Scientific IL17RA Polyclonal Antibody
IL17RA 단백질을 표적하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체. Mouse 및 Rat 시료에 반응하며 Western blot에 적합. 합성 펩타이드 면역원 사용, 액상 형태로 제공. 연구용으로 염증 및 자가면역 질환 관련 분석에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (DQEKHGDDSKIN) corresponding to internal amino acids of IL17RA (aa 353–364) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10984924 |
Product Specific Information
- This antibody is predicted to react with mouse based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 8,000.
Target Information
Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It induces maturation of CD34-positive hematopoietic precursors into neutrophils.
IL-17RA is a type I membrane glycoprotein binding to IL-17A and IL-17F with low affinity.
IL-17A and IL-17RA are involved in inflammatory and autoimmune diseases such as rheumatoid arthritis.
Defects in IL-17RA cause familial candidiasis type 5 (CANDF5), a rare disorder with altered immune responses and impaired fungal clearance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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