Thermo Fisher Scientific DIO2 Polyclonal Antibody
DIO2 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체로, 인간 및 생쥐 시료에 반응합니다. IHC, ICC/IF, Flow Cytometry에 적용 가능하며, 고순도 및 안정적인 액상 형태로 제공됩니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 2–3 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| Flow Cytometry (Flow) | 10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (EVKKHQNQEDRC) corresponding to internal amino acids of DIO2 (aa 181–192) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10977989 |
Product Specific Information
This antibody is predicted to react with human, porcine, and rat based on sequence homology.
Tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine via outer ring deiodination to bioactive 3,3’,5-triiodothyronine. The 3′ UTR of Sec-containing genes has a common stem-loop structure, the Sec insertion sequence, necessary for recognition of UGA as a Sec codon rather than a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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