Thermo Fisher Scientific Human RIM3 Synthetic Peptide
인간 RIM3 단백질의 N-말단 17개 아미노산 서열에 해당하는 합성 펩타이드. 항체 차단 실험용으로 사용 가능하며, PBS(pH 7.2)와 0.1% BSA 용액에 200 µg/mL 농도로 제공. 신경 전달 및 가소성 연구에 활용 가능.
- 카탈로그번호
- PEP0595
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 17 amino acids near the amino terminus of human Rim3.
PEP-0595 can be used as a blocking peptide with polyclonal antibody PA5-20475.
Target Information
Rab3-interacting molecules (RIMs) are synaptic proteins necessary for neural transmission and plasticity. While both Rim1 and Rim2 are thought to be effector proteins for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner, less is known of Rim3.
Expression of Rim3 in PC12 cells induced a significant increase in calcium-triggered exocytosis, with no appreciable change in the baseline release, suggesting that it plays a role in the regulation of exocytosis.
Rim3 protein localizes primarily to neuronal dendrites and the postsynaptic densities, as opposed to Rim1 which is found in presynapse locations, indicating that Rim3 may contribute to synapse transmission and plasticity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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