Thermo Fisher Scientific SESN1 Polyclonal Antibody
Human SESN1 단백질에 특이적인 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제됨. PBS 기반 보존액과 40% 글리세롤 포함, 장기보관 시 -20°C에서 안정적 저장 가능.
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Thermo Fisher Scientific SESN1 Polyclonal Antibody
Applications
- Immunocytochemistry (ICC/IF)
Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein corresponding to Human SESN1. Recombinant protein control fragment (Product #RP-107941) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2857122 |
Product Specific Information
Immunogen sequence:
ASRFEIEKRE SMFVFSSDDE EVTPARAVSR HFEDTSYGYK DFSRHGMHVP TFRVQDYC
Target Information
This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress.
The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase (AMPK), which results in inhibition of the mammalian target of rapamycin (mTOR) protein.
It also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation.
Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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