Thermo Fisher Scientific TRIB1 Monoclonal Antibody (OTI8C8), TrueMAB
TRIB1 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot 및 IHC(P) 분석에 적합. 고순도 친화 크로마토그래피 정제, PBS/BSA/glycerol 저장 버퍼. 인간 시료 반응성, 연구용 전용 제품.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific TRIB1 Monoclonal Antibody (OTI8C8), TrueMAB
Applications
- Western Blot (WB): 1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8C8 |
| Immunogen | Full length human recombinant protein of human TRIB1 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
TRIB1 (also known as gprotein coupled receptor induced, skip1, gig2, c8fwATP) functions in protein binding, protein kinase inhibitor activity, and protein serine/threonine kinase activities.
Overexpression of TRIB1 in HeLa cells represses IL8 promoter basal activity by inhibiting AP1 activity.
TRIB1 inhibits oncogenic Ras-driven AP1 activation and MEKK1-mediated AP1 activation, while enhancing ERK activation.
Coimmunoprecipitation and yeast two-hybrid assays show that MEK1 interacts with both TRIB1 and TRIB3, and MKK4 interacts specifically with TRIB1.
Cotransection of MKK4 enhances TRIB1 levels, indicating that TRIB-MAPKK interaction stabilizes TRIB1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.