Thermo Fisher Scientific IP3 Receptor 1 Polyclonal Antibody
IP3 Receptor 1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 면역조직화학(IHC) 분석에 적합합니다. 인간, 생쥐, 랫드 등 다양한 종에 높은 반응성을 보이며, ER 칼슘 방출 및 세포자멸 조절 연구에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:1,000 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:1,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of mouse IP3 Receptor I |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.72 mg/mL |
| Storage Conditions | Store at 4°C for short term. For long term storage, store at -20°C and avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792902 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Human (98%), Mouse (100%), Rat (100%), Chicken (84%), Bovine (96%).
- Positive control: Mouse brain, Rat brain.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The IP3 Receptor 1 is an intracellular calcium channel that mediates calcium release from the endoplasmic reticulum upon stimulation by inositol 1,4,5-trisphosphate. It regulates epithelial electrolyte and fluid secretion through interaction with AHCYL1 and plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER activates CaM kinase II, leading to downstream apoptotic pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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