Thermo Fisher Scientific L1/ORF2 Polyclonal Antibody
Thermo Fisher Scientific L1/ORF2 Polyclonal Antibody는 Mouse L1/ORF2 단백질을 인식하는 Chicken IgY 기반 항체로, ELISA 등 다양한 연구용 분석에 적합합니다. Endonuclease domain 특이적 반응성을 가지며, 장기 보관 시 안정성이 우수합니다.
- 카탈로그번호
- 200-901-P11x (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific L1/ORF2 Polyclonal Antibody
Applications
- ELISA (ELISA)
Tested Dilution
- 1:20,000–1:100,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Chicken / IgY |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | This IgY fraction antibody was prepared from eggs of chickens laid after repeated immunizations with three synthetic peptides conjugated to keyhole limpet hemocyanin (KLH). The peptides correspond to regions within the endonuclease domain of L1/ORF2 protein. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.21 mg/mL |
| Purification | Selective precipitation |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use.
Anti-L1/ORF2 Antibody is directed against three regions within the endonuclease domain of L1 ORF2 protein. Reactivity occurs against mouse L1/ORF2 protein and is useful in determining its presence in various assays.
A BLAST analysis shows reactivity with L1/ORF2 proteins from mouse sources based on 100% homology with the immunizing sequences. Cross-reactivity against L1/ORF2 from other sources is unknown.
Target Information
The L1 (LINE-1), or Long INterspersed Element, retrotransposon ORF2 is the most common open reading frame in the human genome, present in various forms in many thousands of copies.
This large family of proteins includes magnesium-dependent endonucleases and a large number of phosphatases involved in intracellular signaling.
Both intact ORF1 and ORF2 are absolutely required for autonomous retro-transposition. ORF2 encodes endonuclease, reverse transcriptase, and zinc knuckle domains.
Expression of ORF2 appears to be tightly regulated except in germ line tissues, embryonic tissues, and certain cancers including teratomas, testicular cancers, and leukemias.
This antibody is intended for use in studying control of L1 retrotransposons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.