Thermo Fisher Scientific HCG-beta Monoclonal Antibody (HCGb, 459)
인간 hCG 베타 단백질을 인식하는 마우스 단클론 항체로, 파라핀 포매 조직의 면역조직화학(IHC) 실험에 적합합니다. 비결합형 액상 포맷이며 Protein A/G로 정제되었습니다. PBS 버퍼에 0.05% BSA와 sodium azide를 포함하고 4°C에서 보관합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | HCGb, 459 |
| Immunogen | Recombinant full-length hCG beta protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed):
Incubate antibody for 30 minutes at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
hCG beta is the beta chain of human chorionic gonadotropin (hCG), a 40 kDa glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10–12 days after conception.
hCG consists of alpha and beta subunits that are non-covalently associated. The alpha subunit is similar to those found in pituitary hormones (FSH, LH, TSH), while the beta subunit confers biological specificity.
During early pregnancy, hCG maintains the corpus luteum, stimulating progesterone production to support the endometrium.
In non-pregnant individuals, hCG is present only in trace amounts but rises sharply during pregnancy.
Diseases associated with hCG dysfunction include gestational trophoblastic tumor and hydatidiform mole.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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