Thermo Fisher Scientific LCAT Monoclonal Antibody (C5)

Applications

Tested Dilution

Publications

Western Blot (WB)

0.5-5 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

5-30 µg/mL

-

Immunohistochemistry (Frozen) (IHC (F))

5-30 µg/mL

-

Immunocytochemistry (ICC/IF)

5-30 µg/mL

-

ELISA (ELISA)

0.05-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b, kappa

Class

Monoclonal

Type

Antibody

Clone

C5

Immunogen

Recombinant protein Lecithin Cholesterol Acyltransferase. The antigen corresponds to amino acid range 290-433 of the target protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LCAT,uniProtId:P04180-1,ncbiNodeId:9606,antigenRange:290-433,antigenLength:440,antigenImageFileName:MA5-41625_LCAT_P04180-1_House_mouse.svg,antigenImageFileNamePDP:MA5-41625_LCAT_P04180-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A/G

Storage buffer

PBS with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2899107

Target Information

Lecithin: cholesterol acyltransferase (LCAT) is the plasma enzyme responsible for most HDL cholesteryl esters in human plasma. In species with cholesteryl ester transfer protein (CETP) it is also responsible for a significant proportion of VLDL and LDL cholesteryl esters. LCAT, through the esterification of cholesterol, plays a role in the reverse cholesterol transport pathway by facilitating the net movement of cholesterol from peripheral tissues back to the liver for excretion. LCAT deficiency results in low levels of plasma HDL, whereas a transgenic overexpression of LCAT results in increased plasma HDL concentrations.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.