Thermo Fisher Scientific SNX4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human SNX4. Recombinant protein control fragment (Product #RP-102402). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SNX4,uniProtId:O95219-1,ncbiNodeId:9606,antigenRange:238-386,antigenLength:450,antigenImageFileName:PA5-52188_SNX4_O95219-1_Rabbit.svg,antigenImageFileNamePDP:PA5-52188_SNX4_O95219-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2647729

Product Specific Information

Immunogen sequence: LRVRARVADR LYGVYKVHGN YGRVFSEWSA IEKEMGDGLQ SAGHHMDVYA SSIDDILEDE EHYADQLKEY LFYAEALRAV CRKHELMQYD LEMAAQDLAS KKQQCEELVT GTVRTFSLKG MTTKLFGQET PEQREARIKV LEEQINEGE

Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 99%.

Target Information

SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain. These proteins are all partially associated with cellular membranes, and they, likewise, associate with EGF, PDGF and insulin receptor tyrosine kinases. These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multisubunit complexes. The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.