Thermo Fisher Scientific PDCD6 Polyclonal Antibody
PDCD6 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Human, Mouse, Rat에 반응합니다. Western blot, ELISA, Immunoprecipitation에 사용 가능하며, 고순도 친화성 크로마토그래피로 정제된 액상 항체입니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Immunoprecipitation (IP)
- Tested Dilution: 0.5 µg–4 µg antibody for 200 µg–400 µg extracts
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1–191 of human PDCD6 (NP_037364.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.90 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855496 |
Product Specific Information
Immunogen sequence:
MAAYSYRPGP GAGPGPAAGA ALPDQSFLWN VFQRVDKDRS GVISDTELQQ ALSNGTWTPF NPVTVRSIIS MFDRENKAGV NFSEFTGVWK YITDWQNVFR TYDRDNSGMI DKNELKQALS GFGYRLSDQF HDILIRKFDR QGRGQIAFDD FIQGCIVLQR LTDIFRRYDT DQDGWIQVSY EQYLSMVFSI V
Target Information
An increased intracellular Ca²⁺ concentration induces apoptotic cell death. Transiently elevated Ca²⁺ concentrations are required for glucocorticoid-mediated and T cell receptor-mediated pathways, leading to T cell apoptosis.
ALG-2 (apoptosis-linked gene 2) is a Ca²⁺-binding protein that participates in regulatory events occurring late in the apoptotic program, where several death signals converge. ALG-2 is expressed in normal brain and more abundantly in ischemic brain. The protein contains five EF-hand-like motifs and shares homology with penta EF-hand family members, including Calpain small subunits sorcin and Grancalcin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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