Thermo Fisher Scientific PDCD6 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:1,000

ELISA

• Tested Dilution: 1 µg/mL

Immunoprecipitation (IP)

• Tested Dilution: 0.5 µg–4 µg antibody for 200 µg–400 µg extracts

Product Specifications

Product Specific Information

Immunogen sequence:
MAAYSYRPGP GAGPGPAAGA ALPDQSFLWN VFQRVDKDRS GVISDTELQQ ALSNGTWTPF NPVTVRSIIS MFDRENKAGV NFSEFTGVWK YITDWQNVFR TYDRDNSGMI DKNELKQALS GFGYRLSDQF HDILIRKFDR QGRGQIAFDD FIQGCIVLQR LTDIFRRYDT DQDGWIQVSY EQYLSMVFSI V

Target Information

An increased intracellular Ca²⁺ concentration induces apoptotic cell death. Transiently elevated Ca²⁺ concentrations are required for glucocorticoid-mediated and T cell receptor-mediated pathways, leading to T cell apoptosis.
ALG-2 (apoptosis-linked gene 2) is a Ca²⁺-binding protein that participates in regulatory events occurring late in the apoptotic program, where several death signals converge. ALG-2 is expressed in normal brain and more abundantly in ischemic brain. The protein contains five EF-hand-like motifs and shares homology with penta EF-hand family members, including Calpain small subunits sorcin and Grancalcin.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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