Thermo Fisher Scientific Contactin 2 Polyclonal Antibody
Contactin 2 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 ELISA에 사용 가능. Mouse와 Rat 시료에 반응하며, 고순도의 Affinity Chromatography 정제. PBS/glycerol buffer에 보존되어 안정적이며, 신경세포막 단백질 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 785–1012 of human Contactin 2 (NP_005067.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.37 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914705 |
Product Specific Information
Positive test controls include: Mouse brain, Mouse spinal cord, Rat brain.
The target is usually found in the following locations: Cell membrane, GPI-anchor, Lipid-anchor.
Immunogen sequence:
EVKIRSYNRR GDGPESLTAL VYSAEEEPRV APTKVWAKGV SSSEMNVTWE PVQQDMNGIL LGYEIRYWKA GDKEAAADRV RTAGLDTSAR VSGLHPNTKY HVTVRAYNRA GTGPASPSAN ATTMKPPPRR PPGNISWTFS SSSLSIKWDP VVPFRNESAV TGYKMLYQND LHLTPTLHLT GKNWIEIPVP EDIGHALVQI RTTGPGGDGI PAEVHIVRNG GTSMMVEN
Target Information
Contactin 2 (CNTN2, transiently-expressed axonal glycoprotein, AXT, TAX, TAX1, TAG-1, axonin 1) is a neuronal cell adhesion molecule (CAM) that influences the formation of axon connections in the developing nervous system. It belongs to the immunoglobulin superfamily (IgSF) and contains a glycosylphosphatidylinositol-anchor, six immunoglobulin (Ig)-like and four fibronectin type III (FNIII)-like domains.
Contactin 2 is expressed predominantly during neural development on the cell membrane of axons in nerve fiber tracts to guide commissural axons. It binds with NgCAM in the same membrane (cis-binding).
Heterophilic (Contactin 2/NgCAM and Contactin 2/NrCAM) binding sites are localized to the first four Ig domains, while the homophilic (Contactin 2/Contactin 2) binding site is localized to the FNIII domain.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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