Thermo Fisher Scientific Unc18-2 Polyclonal Antibody
Unc18-2 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot과 ELISA에 사용 가능하며, 고순도 Affinity Chromatography로 정제되었습니다. PBS/glycerol buffer에 보관되며 연구용으로 적합합니다.
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Applications
Western Blot (WB)
- Tested dilution: 1:500–1:2,000
ELISA
- Tested concentration: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–280 of human STXBP2 (NP_001120868.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.89 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914704 |
Product Specific Information
- Positive test controls: Mouse thymus, Rat fat
- Immunogen sequence:
MAPSGLKAVV GEKILSGVIR SVKKDGEWKV LIMDHPSMRI LSSCCKMSDI LAEGITIVED INKRREPIPS LEAIYLLSPT EKALIKDFQG TPTFTYKAAH IFFTDTCPEP LFSELGRSRL AKVVKTLKEI HLAFLPYEAQ VFSLDAPHST YNLYCPFRAE ERTRQLEVLA QQIATLCATL QEYPAIRYRK GPEDTAQLAH AVLAKLNAFK ADTPSLGEGP EKTRSQLLIM DRAADPVSPL LHELTFQAMA YDLLDIEQDT YRYETTGLSE AREKAVLLDE
Target Information
This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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