Thermo Fisher Scientific MGMT Monoclonal Antibody (OTI17H4), TrueMAB
MGMT 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western blot에 최적화됨. 인간 MGMT 재조합 단백질을 면역원으로 제작. 동결건조 형태로 제공되며, 1 mg/mL 농도. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI17H4 |
| Immunogen | Full length human recombinant protein of human MGMT produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
O6-Methylguanine-DNA Methyltransferase (MGMT) is a DNA repair protein that contributes to tumor cell resistance against alkylating chemotherapeutic agents. MGMT removes alkyl groups from the O6 position of guanine, protecting both normal and tumor cells from genotoxic effects. Expression levels vary by tissue type, species, and growth conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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