Thermo Fisher Scientific Phospho-C-rel (Ser492, Ser460) Polyclonal Antibody
Rabbit polyclonal antibody recognizing phosphorylated c-Rel at Ser492 and Ser460. Validated for Western blot (1:1,000–1:3,000). Detects endogenous phosphorylated Rel isoforms. Supplied as liquid, 1 mg/mL, stored at -20°C. For research use only.
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Applications
- Western Blot (WB): 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human REL (Accession Q04864), corresponding to amino acid residues around phosphorylated Ser492. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2816013 |
Product Specific Information
This antibody detects endogenous levels of Rel only when phosphorylated at Ser492 (Isoform 1, Q04864-1) or Ser460 (Isoform 2, Q04864-2).
Target Information
The REL gene encodes c-Rel, a transcription factor belonging to the Rel/NFκB family, which includes RELA, RELB, NFKB1, and NFKB2. These proteins share a conserved N-terminal Rel domain, responsible for DNA binding, dimerization, nuclear localization, and interaction with NFκB inhibitors (Belguise and Sonenshein, 2007).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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