Thermo Fisher Scientific C5aR2 (extracellular) Polyclonal Antibody
C5aR2 단백질의 extracellular 영역을 인식하는 Rabbit Polyclonal 항체로, Mouse 및 Rat 시료에 반응합니다. Western blot, IHC(F), Flow cytometry에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- AAR-034-xxxxx (3개 옵션)
- 판매단위
- pk
카탈로그
3개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific C5aR2 (extracellular) Polyclonal Antibody
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:400 |
| Flow Cytometry (Flow) | 2.5 µg |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | (C)RRLLQEHYPPRLV(S)G, corresponding to amino acid residues 179–193 of mouse C5aR2 (Extracellular, 2nd loop) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitution: Add 25 µL, 50 µL, or 0.2 mL double distilled water (DDW) depending on sample size.
The antibody ships as a lyophilized powder at room temperature. Upon arrival, store at -20°C.
Reconstituted solution can be stored at 4°C for up to 1 week. For longer storage, aliquot and keep at -20°C.
Avoid multiple freeze/thaw cycles. Centrifuge all antibody preparations before use (10,000 × g, 5 min).
Target Information
C5AR2 is a member of the anaphylatoxin receptor family and is a seven-transmembrane G-protein-coupled receptor.
It includes an N-terminal N-glycosylation site, conserved cysteines, and potential C-terminal phosphorylation sites.
C5AR2 binds to C5a and C5a-des-Arg, functioning as a regulated scavenger receptor with negative modulation of C5aR-mediated inflammation.
Northern blot analysis shows co-expression with C5aR in various tissues and cells including neutrophils/macrophages, mast cells, dendritic cells, brain, lung, heart, kidney, liver, ovary, and testis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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