Thermo Fisher Scientific TAP1 Recombinant Rabbit Monoclonal Antibody (6Q8Q5)
TAP1 단백질을 인식하는 토끼 유래 재조합 단클론 항체로, Western blot 및 ELISA에 최적화됨. 인간, 마우스, 랫트 반응성. HEK293 세포에서 발현, Protein A로 정제된 고순도 항체. 연구용으로 TAP1 관련 면역학 및 단백질 수송 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 6Q8Q5 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 449–748 of human TAP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.16 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
Product Specific Information
Immunogen Sequence:
LYQMQFTQAV EVLLSIYPRV QKAVGSSEKI FEYLDRTPRC PPSGLLTPLH LEGLVQFQDV SFAYPNRPDV LVLQGLTFTL RPGEVTALVG PNGSGKSTVA ALLQNLYQPT GGQLLLDGKP LPQYEHRYLH RQVAAVGQEP QVFGRSLQEN IAYGLTQKPT MEEITAAAVK SGAHSFISGL PQGYDTEVDE AGSQLSGGQR QAVALARALI RKPCVLILDD ATSALDANSQ LQVEQLLYES PERYSRSVLL ITQHLSLVEQ ADHILFLEGG AIREGGTHQQ LMEKKGCYWA MVQAPADAPE
Target Information
The membrane-associated protein encoded by this gene belongs to the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes and are divided into seven subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is part of the MDR/TAP subfamily, which is involved in multidrug resistance. It plays a role in pumping degraded cytosolic peptides across the endoplasmic reticulum for class I molecule assembly. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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