Thermo Fisher Scientific ABHD3 Polyclonal Antibody
ABHD3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간, 마우스, 랫트에 반응하며 IHC, ICC/IF, ELISA 등 다양한 응용 가능. 고순도 Protein A 정제, 안정적인 액상 형태로 연구용에 최적화.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human ABHD3, amino acids 201–285 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The α/β hydrolase superfamily comprises diverse members involved in important biochemical processes and various diseases. Despite differing sequences and substrates, they share a canonical α/β hydrolase fold with an eight-stranded parallel α/β structure and a catalytic triad (histidine, acid, nucleophile). Members of this superfamily are often drug targets for diseases such as diabetes, Alzheimer’s disease, obesity, and blood clotting disorders.
The α/β hydrolase domain containing (ABHD) gene subfamily includes 15 mostly uncharacterized members, most of which utilize a serine nucleophile to form the G-X-S-X-G nucleophile elbow.
- ABHD1 plays a role in metabolizing smoking xenobiotics.
- ABHD2 participates in the development of atherosclerosis.
- ABHD3 is a 409 amino acid single-pass type II membrane protein.
- ABHD4 is involved in an alternative synthesis pathway of NAE (N-acyl ethanolamine).
- ABHD5 mutations contribute to Chanarin-Dorfman syndrome.
- ABDH6 may play a role in nervous system metabolism and signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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