Thermo Fisher Scientific Dynein Polyclonal Antibody
Dynein 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot과 ELISA에 적합하며, 액상 형태로 제공됩니다. 세포 내 세포골격 연구 및 단백질 수송 메커니즘 분석에 유용합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–89 of human DYNLL2 (NP_5424081) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.18 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805618 |
Product Specific Information
- Immunogen sequence:
MSDRKAVIKN ADMSEDMQQD AVDCATQAME KYNIEKDIAA YIKKEFDKKY NPTWHCIVGR NFGSYVTHET KHFIYFYLGQ VAILLFKSG - Positive Samples: Mouse brain, Mouse kidney, Rat brain
- Cellular Location: Cytoplasm, cytoskeleton
Target Information
The directed movement of membrane-bounded organelles is crucial for cellular functions such as membrane transport, secretion, and axonal transport. Cytoplasmic dynein, a minus end-directed microtubule-based motor protein, is responsible for retrograde transport of membranous organelles from the synapse to the cell body during fast axonal transport. The dynein complex consists of two ~530 kDa heavy chains and intermediate chains of ~74 kDa and ~53–59 kDa.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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