Thermo Fisher Scientific AMACR Monoclonal Antibody (1D8)
AMACR 단백질을 인식하는 Mouse IgG2b 단일클론 항체로, Western blot 및 ELISA에 적합합니다. 인간 시료 반응성이 있으며, 액상 형태로 제공됩니다. 연구용으로만 사용되며, 고순도 친화 크로마토그래피로 정제되었습니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 1 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1D8 |
| Immunogen | AMACR (AAH09471, 1–198 a.a) full-length recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MALQGISVME LSGLAPGPFC AMVLADFGAR VVRVDRPGSR YDVSRLGRGK RSLVLDLKQP RGAAVLRRLC KRSDVLLEPF RRGVMEKLQL GPEILQRENP RLIYARLSGF GQSGSFCRLA GHDINYLALS GGRNSMFKFF SVENSEIESV GSTSRTEHVG WWSTFLYDLQ DSRWGIHGCW SNRTPVLRAA DQRTWTKV
Target Information
P504S/AMACR (α-Methylacyl-CoA Racemase) is an essential enzyme in the β-oxidation of branched-chain fatty acids.
High expression of P504S protein is found in prostatic adenocarcinoma but not in benign prostate tissue by immunohistochemical staining in paraffin-embedded tissue.
The expression of P504S is also detected in two premalignant lesions of the prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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