Thermo Fisher Scientific PADI4 Monoclonal Antibody (4D8)
PADI4 단백질을 인식하는 Mouse monoclonal antibody (Clone 4D8). Western blot, ICC/IF, ELISA에 사용 가능. Human 시료 반응성. PBS buffer에 보존된 액상 형태로 제공되며, -20°C에서 보관 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4D8 |
| Immunogen | PADI4 (NP_004247, 2 a.a. ~110 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
AQGTLIRVTP EQPTHAVCVL GTLTQLDICS SAPEDCTSFS INASPGVVVD IAHSPPAKKK STGSSTWPLD PGVEVTLTMK AASGSTGDQK VQISYYGPKT PPVKALLYL
Target Information
Catalyzes the citrullination/deimination of arginine residues of proteins.
Citrullinates histone H3 at Arg-8 and/or Arg-17 and histone H4 at Arg-3, which prevents their methylation by CARM1 and HRMT1L2/PRMT1 and represses transcription.
Citrullinates EP300/P300 at Arg-2142, which favors its interaction with NCOA2/GRIP1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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