Thermo Fisher Scientific Cadherin 17/LI Cadherin (Liver-Intestine Marker) Recombinant Rabbit Monoclonal Antibody (CDH17/8513R)
인체 CDH17 단백질을 인식하는 재조합 토끼 단클론 항체. IHC(P) 및 IHC(PFA)에서 사용 가능하며, 단백질 A로 정제된 액상 형태. 간·장 조직의 형태학적 연구 및 리버-인테스틴 마커 분석에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | CDH17/8513R |
| Immunogen | Recombinant fragment (around aa 242–418) of human Cadherin 17 protein (CDH17) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
The CDH17 gene belongs to the cadherin superfamily, encoding calcium-dependent, membrane-associated glycoproteins. The protein has an extracellular region with seven cadherin domains and a transmembrane region but lacks the conserved cytoplasmic domain.
It is expressed in the gastrointestinal tract and pancreatic ducts, functioning as an intestinal proton-dependent peptide transporter involved in the absorption of peptide-based drugs.
Additionally, CDH17 may play a role in the morphological organization of the liver and intestine.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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