Thermo Fisher Scientific Human CAMK2B (CaMKII Beta), His Tag Recombinant Protein

Applications

• Kinase Assay (KA)

Tested Dilution: Assay-dependent
Publications: N/A

Product Specifications

Product Specific Information

• For maximum recovery, please spin prior to use.
• Aliquots of 5 µg, 10 µg, and 20 µg sizes are not recommended; use original packaging until exhausted.
• For larger sizes, reduce freeze/thaws by preparing aliquots (not below 20 µL).
• Do not store kinase diluted.
• Properly stored at -80°C, product is guaranteed for 6 months from date of purchase.

Protein Form: Full Length

Target Information

CAMK2B (CaMKII beta) is a serine/threonine kinase involved in synaptic plasticity, synaptic vesicle mobilization, and regulation of gene expression. It functions as a dominant kinase in the central nervous system, contributing to long-term potentiation and neurotransmitter release.
There are four CaMKII isozymes—alpha, beta, gamma, and delta—which may be co-expressed in the same tissue type. CaMKII alpha is autophosphorylated on Thr286 upon Ca²⁺/CaM binding to its autoinhibitory domain, a process known as Ca²⁺/CaM trapping, thought to be involved in synaptic information encoding.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.