Thermo Fisher Scientific AEBP1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.2-2.5 µg/mL

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Immunohistochemistry (Paraffin) (IHC (P))

2-10 µg/mL

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Product Specifications

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide region of human AEBP1.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2225958

Product Specific Information

Recommended positive controls: HepG2.

Predicted reactivity: Cow: 92%; Dog: 92%; Guinea Pig: 100%; Horse: 100%; Mouse: 92%; Rabbit: 100%; Rat: 100%.

By Western blot, PA1-24440 detects a ~ 131 kDa protein representing AEBP1 in HepG2cell lysate.

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

The adipocyte enhancer binding protein 1 (AEBP1) is a transcriptional repressor with carboxypeptidase (CP) activity. This protein binds to a regulatory sequence, adipocyte enhancer 1 (AE-1), located in the proximal promoter region of the adipose P2 (aP2) gene, which encodes the adipocyte fatty-acid binding protein. It is characterized as a member of the regulatory B-like CP family. This protein seems to be activated by a novel mechanism, whereby the direct binding of DNA enhances its protease activity. AEBP1 may play a role in differentiated vascular smooth muscle cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.