Thermo Fisher Scientific FOXJ1 Polyclonal Antibody
FOXJ1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간·마우스·랫에서 반응합니다. Western blot에 최적화되어 있으며, 액상 형태로 제공되고 항원 친화 크로마토그래피로 정제되었습니다. FOXJ1 관련 면역 및 섬모 형성 연구에 적합합니다.
- 카탈로그번호
- 720226
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptides corresponding to human FOXJ1 (aa267–aa284, aa403–aa421) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 30% glycerol, 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2664304 |
Product Specific Information
This antibody is predicted to react with Monkey, Bovine, and Pig.
Target Information
Forkhead-box J1 (FOXJ1) is a 421-amino acid transcription factor that suppresses T cell activity and spontaneous autoimmunity through repression of NF-κB activity. It also inhibits humoral immune response in B cells. FOXJ1 deficiency in B cells leads to spontaneous and accentuated germinal center formation, contributing to pathogenic autoantibody development and enhanced immunization responses. Abnormal FOXJ1 expression may be associated with autoimmune or inflammatory diseases. FOXJ1 is also essential for cilia formation and left-right axis determination by increasing calpastatin expression, which anchors basal bodies to the apical cytoskeleton. FOXJ1 expression serves as an early marker of epithelial cell differentiation, recovery, and function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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