Thermo Fisher Scientific CDC37 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human CDC37 protein. Validated for Western blot and immunoprecipitation. Supplied as liquid, 0.20 mg/mL concentration. Recommended storage at 4°C. For research use only.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 324 to 374 of human cell division cycle 37 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
In S. cerevisiae, Cdc37 has been shown to be an important regulator of the cell division cycle through its action on cyclin-dependent kinases (CDKs).
Cdc37 is also associated with signaling pathways and kinases unrelated to cell cycle control, including v-Src, casein kinase II, MPS1 kinase, and the sevenless receptor tyrosine kinase.
HSP90 has been shown to associate with many of the same cellular targets as Cdc37. Cdc37, also known as p50, forms complexes with Src-family kinases (Fyn, Yes, Fes, Lck, and Fgr), Raf, and pp60v-src.
Cdc37 functions as a chaperone independently and in concert with HSP90, and is necessary for the binding of HSP90 to Cdk4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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