Thermo Fisher Scientific LRP1 Monoclonal Antibody (8G1)
LRP1 단백질을 인식하는 Mouse IgG1 단클론 항체(클론 8G1). Western blot, IHC, Flow cytometry 등 다양한 응용 가능. 인간 및 마우스 반응성. 비결합형 액상 형태로 단백질 A 정제. 단기 4°C, 장기 -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–5 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC-P) | 1–10 µg/mL | - |
| Immunohistochemistry (Frozen) (IHC-F) | 1–10 µg/mL | - |
| Flow Cytometry (Flow) | Assay-dependent | View 1 publication |
| Neutralization (Neu) | - | View 2 publications |
| In vitro Assay (IV) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 8G1 |
| Immunogen | Human LRP/alpha2 MR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.0 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_794778 |
Product Specific Information
- Perform Western blot analysis under non-reducing conditions.
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is an endocytic receptor involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells.
It is necessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients.
Expression of this gene decreases with age and is lower than controls in brain tissue from Alzheimer patients.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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