Thermo Fisher Scientific APBB1 Monoclonal Antibody (OTI1G6), TrueMAB
인간 APBB1 단백질을 인식하는 마우스 단클론 항체로 Western blot에 적합합니다. TrueMAB 형식으로 제작되었으며, 1 mg/mL 농도의 액상 형태입니다. PBS, BSA 및 글리세롤 완충액에 보관되며, -20°C에서 냉동 보관합니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G6 |
| Immunogen | Full length human recombinant protein of human APBB1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a member of the Fe65 protein family and functions as a nuclear adaptor protein. It interacts with the Alzheimer’s disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1, and the low-density lipoprotein receptor-related protein. APP serves as a cytosolic anchoring site that can prevent nuclear translocation of this gene product. This protein may play an important role in the pathogenesis of Alzheimer’s disease and is thought to regulate transcription. It may also block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants have been described for this gene, though some full-length sequences are not fully known.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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