Thermo Fisher Scientific PLEKHM2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.5 µg/mL

View 2 publications 2 publications

Immunohistochemistry (IHC)

5 µg/mL

-

Immunocytochemistry (ICC/IF)

20 µg/mL

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A 17 amino acid peptide from near the carboxy terminus of human PLEKHM2. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PLEKHM2,uniProtId:Q8IWE5-1,ncbiNodeId:9606,antigenRange:1019,antigenLength:1019,antigenImageFileName:PA5-20850_PLEKHM2_Q8IWE5-1_Rabbit.svg,antigenImageFileNamePDP:PA5-20850_PLEKHM2_Q8IWE5-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_11153975

Product Specific Information

A suggested positive control is rat brain tissue lysate.

PA5-20850 can be used with blocking peptide PEP-0964.

Target Information

PLEKHM2, also known as SKIP, is a member of the M family of Pleckstrin homology domain-containing proteins. While little is known of PLEKHM2, a recent study examining differential gene expression in human hematopoietic stem cells has shown it to be specifically expressed in stem cells, suggesting that PLEKHM2 may play a role in erythroid commitment and development. Other studies have shown that PLEKHM2 is required for interaction with the Salmonella virulence factor SifA for Salmonella pathogenesis, suggesting that PLEKHM2 has cellular roles other than in the developing embryo.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.