Thermo Fisher Scientific PCDHGA5 Polyclonal Antibody, MaxPab

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MASPPRGWGC GELLLPFMLL GTLCEPGSGQ IRYSMPEELD KGSFVGNIAK DLGLEPQELA ERGVRIVSRG RTQLFALNPR SGSLVTAGRI DREELCAQSP LCVVNFNILV ENKMKIYGVE VEIIDINDNF PRFRDEELKV KVNENAAAGT RLVLPFARDA DVGVNSLRSY QLSSNLHFSL DVVSGTDGQK YPELVLEQPL DREKETVHDL LLTALDGGDP VLSGTTHIRV TVLDANDNAP LFTPSEYSVS VPENIPVGTR LLMLTATDPD EGINGKLTYS FRNEEEKISE TFQLDSNLGE ISTLQSLDYE ESRFYLMEVV AQDGGALVAS AKVVVTVQDV NDNAPEVILT SLTSSISEDC LPGTVIALFS VHDGDSGENG EIACSIPRNL PFKLEKSVDN YYHLLTTRDL DREETSDYNI TLTVMDHGTP PLSTESHIPL KVADVNDNPP NFPQASYSTS VTENNPRGVS IFSVTAHDPD SGDNARVTYS LAEDTFQGAP LSSYVSINSD TGVLYALRSF DYEQLRDLQL WVTASDSGNP PLSSNVSLSL FVLDQNDNTP EILYPALPTD GSTGVELAPR SAEPGYLVTK VVAVDKDSGQ NAWLSYRLLK ASEPGLFAVG LHTGEVRTAR ALLDRDALKQ SLVVAVEDHG QPPLSATFTV TVAVADRIPD ILADLGSIKT PIDPEDLDLT LYLVVAVAAV SCVFLAFVIV LLVLRLRRWH KSRLLQAEGS RLAGVPASHF VGVDGVRAFL QTYSHEVSLT ADSRKSHLIF PQPNYADTLL SEESCEKSEP LLMSDKVDAN KEERRVQVSF LFR

Target Information

This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.