Thermo Fisher Scientific IL10RA Monoclonal Antibody (4D3A9)
IL10RA 단백질을 인식하는 mouse monoclonal antibody로 Western blot, Flow cytometry, ELISA에 적합. Human 시료 반응성, Protein G 정제, PBS buffer에 0.05% sodium azide 포함. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4D3A9 |
| Immunogen | Purified recombinant fragment of human CD210 (AA: 22–235) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090723 |
Target Information
The protein encoded by this gene is a receptor for interleukin 10. It is structurally related to interferon receptors and mediates the immunosuppressive signal of interleukin 10, thereby inhibiting the synthesis of proinflammatory cytokines. This receptor promotes survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants have been identified: one protein-coding and one non-coding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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