Thermo Fisher Scientific TAF12 Monoclonal Antibody (22TA-2A1)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunocytochemistry (ICC/IF)

1:2,000

-

Flow Cytometry (Flow)

1:100

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

22TA-2A1

Immunogen

Recombinant human TAF12 protein. Epitope localized at the C-terminal part of TAF12. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TAF12,uniProtId:Q16514-1,ncbiNodeId:9606,antigenRange:161,antigenLength:161,antigenImageFileName:MA3-072_TAF12_Q16514-1_House_mouse.svg,antigenImageFileNamePDP:MA3-072_TAF12_Q16514-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

ascites

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2633319

Product Specific Information

MA3-072 detects TATA-Binding Protein (TBP) Associated factor 12 in the human samples.

MA3-072 has been successfully used in Western blot, immunofluorescence, and flow cytometry applications.

The MA3-072 immunogen is a recombinant human TAF12 protein. Epitope is localized at the C-terminal part of TAF12.

Target Information

TAF12 is involved in the control of transcription by RNA polymerase II involves the basal transcription machinery which is a collection of proteins. These proteins with RNA polymerase II, assemble into complexes which are modulated by transactivator proteins that bind to cis-regulatory elements located adjacent to the transcription start site. Some modulators interact directly with the basal complex, whereas others may act as bridging proteins linking transactivators to the basal transcription factors. Some of these associated factors are weakly attached while others are tightly associated with TBP in the TFIID complex. Among the latter are the TAF proteins. Different TAFs are predicted to mediate the function of distinct transcriptional activators for a variety of gene promoters and RNA polymerases. TAF12 interacts directly with TBP as well as with TAF2I.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.