Thermo Fisher Scientific TCF2 Polyclonal Antibody
Rabbit polyclonal antibody targeting TCF2 (HNF1b) for WB, IHC, ICC, IP, and ChIP applications. Reacts with human, mouse, and rat. Affinity-purified, unconjugated, and supplied in PBS with BSA and glycerol. For research use only.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | – |
| Immunohistochemistry (Frozen) (IHC (F)) | – | 1 publication |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | – |
| Immunoprecipitation (IP) | – | 1 publication |
| ChIP assay (ChIP) | 1.5 µg/10^6 cells | – |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptides corresponding to Human HNF1b (aa 511–528, 191–208) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA, 30% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2633221 |
Product Specific Information
These polyclonal antibodies are of rabbit origin and developed by immunizing animals with specific proteins or peptides. The antibody is purified by affinity chromatography from rabbit sera and tested for functionality in relevant research applications.
Predicted to react with Monkey, Horse, and Cat.
For Research Use Only. Non-hazardous and non-infectious.
Target Information
Hepatocyte Nuclear Factor 1 (HNF1, Homeoprotein LFB3, Transcription Factor 2, TCF2) is a homeodomain-containing transcription factor. It functions as a liver-specific regulator and can form homodimers or heterodimers with HNF1-alpha.
HNF1 plays a role in nephron and pancreatic development. Mutations in this gene are linked to renal cysts and diabetes syndromes, and its expression is altered in certain cancers. Multiple transcript variants encoding different isoforms exist.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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