Thermo Fisher Scientific CD147 Polyclonal Antibody
Rabbit polyclonal antibody targeting human CD147, suitable for WB, IHC, IHC-P, and IP applications. Liquid form, unconjugated, 1 mg/mL concentration. Recommended for research use only, stored at 4°C. Recognizes CD147 region 200–250, predicted cross-rea...
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 200–250 of human CD147 antigen |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with bovine
Target Information
CD147 (also known as basigin, neurothelin, OX-47, 5A11, CE9, M6, EMMPRIN, extracellular matrix metalloproteinase inducer, TCSF, tumour cell-derived collagenase-stimulatory factor) is a 50–60 kDa glycoprotein with multiple glycosylated forms.
It is a plasma membrane protein involved in:
- Spermatogenesis
- Embryo implantation
- Neural network formation
- Tumor progression
CD147 belongs to the immunoglobulin superfamily and is highly expressed in metabolically active cells such as lymphoblasts, inflammatory cells, brown adipocytes, and malignant tumor cells.
It facilitates cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulates integrin functions, and plays roles in cell development, activation, fetal development, and retinal function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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