Thermo Fisher Scientific CD147 Polyclonal Antibody
CD147 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, IP 등 다양한 응용에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공. 인간 시료에 반응하며 4°C에서 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 | |
| Immunohistochemistry (IHC) | 1:500–1:2,000 | |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 | |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 200 to 250 of human CD147 Antigen |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Bovine
Target Information
CD147 (also known as basigin, neurothelin, OX-47, 5A11, CE9, M6, EMMPRIN, extracellular matrix metalloproteinase inducer, TCSF) is a 50–60 kDa glycoprotein with multiple glycosylated forms.
It is a plasma membrane protein important in spermatogenesis, embryo implantation, neural network formation, and tumor progression, and is a member of the immunoglobulin superfamily.
CD147 is highly expressed in metabolically active cells such as lymphoblasts, inflammatory cells, brown adipocytes, and malignant tumor cells.
It facilitates the cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulates integrin functions, and plays roles in cell development, activation, fetal development, and retinal function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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