Thermo Fisher Scientific ADH5 Monoclonal Antibody (OTI4H10), TrueMAB
인간 ADH5 단백질(aa 1–266)에 특이적인 단일클론 항체로 Western blot에 최적화됨. Mouse IgG2b 형식이며, 액상 상태로 제공. 고순도 친화 크로마토그래피 정제, 안정적 PBS/BSA/glycerol 저장 버퍼 구성. 연구용으로만 사용 가능.
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Applications
Tested Application & Dilution
- Western Blot (WB): 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4H10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–266 of human ADH5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products.
The encoded protein forms a homodimer and exhibits high activity for oxidation of long-chain primary alcohols and S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione.
This enzyme plays a crucial role in cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis.
The human genome contains several non-transcribed pseudogenes related to this gene.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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