
Thermo Fisher Scientific hnRNP L Monoclonal Antibody (OTI9G7)
Western blot, IHC, ICC/IF에 적합한 hnRNP L 단일클론 항체로 Human과 Mouse 시료에 반응합니다. 고순도 Affinity Chromatography 정제, 액상 형태로 제공되며 안정적인 저장용 PBS 버퍼 포함. 연구용으로 mRNA 관련 단백질 연구에 활용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9G7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 270–502 of HNRNPL produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724464 |
Target Information
Heterogeneous nuclear RNAs (hnRNAs), including mRNA precursors and mature mRNAs, associate with specific proteins to form heterogeneous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L (hnRNP L) is one of the proteins stably associated with hnRNP complexes and, along with other hnRNP proteins, plays a major role in the formation, packaging, processing, and function of mRNA.
hnRNP L is mainly localized in the nucleoplasm as part of the hnRNP complex but has also been identified outside the nucleoplasm. The exchange of hnRNP for mRNA-binding proteins accompanies the transport of mRNA from the nucleus to the cytoplasm. Since hnRNP proteins can shuttle between the nucleus and cytoplasm, they may also have cytoplasmic functions. Two transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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