Thermo Fisher Scientific IL-4 Monoclonal Antibody (BVD4-1D11)
마우스 IL-4를 인식하는 Rat IgG2b 형 단클론 항체로, Flow Cytometry, ELISA, Neutralization 등 다양한 분석에 사용 가능. 비결합형 액상 제형이며, 1 mg/mL 농도로 PBS 및 0.1% sodium azide 포함. 연구용으로만 사용.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
- Publications: View 1 publication
ELISA (ELISA)
- Tested Dilution: Assay-dependent
- Publications: View 7 publications
Neutralization (Neu)
- Tested Dilution: Assay-dependent
- Publications: View publication
Miscellaneous PubMed (Misc)
- Publications: View 3 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Rat / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | BVD4-1D11 |
| Immunogen | Recombinant mouse IL-4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2536385 |
Target Information
Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells and serves as a ligand for the interleukin 4 receptor. IL-4 exhibits a broad range of actions and shares overlapping functions with IL-13 due to receptor binding similarities. STAT6 plays a key role in mediating IL-4’s immune regulatory signals.
The IL-4 gene, along with IL-3, IL-5, IL-13, and CSF2, forms a cytokine gene cluster on chromosome 5q. IL-4 is located near IL-13, and both genes are coordinated by long-range regulatory elements spanning approximately 120 kilobases. IL-4 delta 2 is a known splice variant of IL-4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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