Thermo Fisher Scientific XPO4 Polyclonal Antibody
Rabbit polyclonal antibody against human XPO4 for ICC/IF applications. Recognizes nuclear transport receptor Exportin-4 involved in Smad signaling. Supplied unconjugated in liquid form, affinity purified, and stored in PBS with glycerol. For research u...
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human XPO4. Recombinant protein control fragment (Product #RP-106493) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664690 |
Product Specific Information
Immunogen sequence:
DIHWLILVTGY LLADDTQGET PLIPPEIMEY SIKHSSEVDI NTTLQILGSP GEKASSIPGY NRTDSVIRLL SAILRVSEVE SRAIRADLTH LLSPQMG
Highest antigen sequence identity to the following orthologs:
- Mouse: 98%
- Rat: 98%
Target Information
Nuclear transport receptors of the karyopherin/importin-beta superfamily mediate various transport pathways between nucleus and cytoplasm. Exportin-4 (XPO4) is a novel mammalian member of this family and a RanGTP-binding protein with an N-terminal RanGTP-binding motif. It functions as a nuclear export receptor for eIF-5A and may act as an export adapter in RNA export. XPO4 is also involved in nuclear export of Smad3 and regulation of Smad signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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