
Thermo Fisher Scientific GBA3 Recombinant Rabbit Monoclonal Antibody (008)
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Applications
Tested Dilution
Publications
Immunocytochemistry (ICC/IF)
1:20-1:100
Flow Cytometry (Flow)
1:25-1:100
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit / IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
008
Immunogen
Recombinant Human GBA3 protein (Met1-Leu469) if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
GBA3,
uniProtId:
Q9H227-1,
ncbiNodeId:
9606,
antigenRange:
1-469,
antigenLength:
469,
antigenImageFileName:
MA5-29284_GBA3_Q9H227-1_Rabbit.svg,
antigenImageFileNamePDP:
MA5-29284_GBA3_Q9H227-1_Rabbit_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
View additional formats
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2785177
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Human GBA3.
Target Information
GBA3, or cytosolic beta-glucosidase (EC 3.2.1.21), is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiologic beta-glycoside, suggesting that it may be involved in detoxification of plant glycosides. GBA3 also has significant neutral glycosylceramidase activity (EC 3.2.1.62), suggesting that it may be involved in a nonlysosomal catabolic pathway of glucosylceramide metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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