Thermo Fisher Scientific SCCPDH Polyclonal Antibody
SCCPDH 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(Paraffin)에 적합합니다. Human, Mouse, Rat에 반응하며, 액상 형태로 제공됩니다. Affinity chromatography로 정제되었으며, PBS/glycerol buffer에 보관됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SCCPDH (Accession Q8NBX0), corresponding to amino acid residues L130–F180. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2851991 |
Product Specific Information
Antibody detects endogenous levels of total SCCPDH.
Target Information
SCCPDH (Probable saccharopine dehydrogenase) is a 429 amino acid protein that belongs to the saccharopine dehydrogenase family.
The SCCPDH gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, fruit fly, mosquito, and C. elegans, and maps to human chromosome 1q44.
Chromosome 1 is the largest human chromosome, spanning about 260 million base pairs and comprising approximately 8% of the human genome. It contains around 3,000 genes, and numerous diseases are associated with this chromosome, including Stickler syndrome, Parkinson’s disease, Gaucher disease, and Usher syndrome.
A breakpoint identified in 1q disrupts the DISC1 gene, which is linked to schizophrenia. Aberrations in chromosome 1 are also found in several cancers, including head and neck cancer, malignant melanoma, and multiple myeloma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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